AROMA and mean FD regression

[Mazz]

Hi,

I’ve just started doing fMRI analyses this year, so do take what I say with a grain of salt.

The link below suggests you would still add mean FD as a nuisance regressor at the group-level (fmriprep also uses ICA-AROMA).

Confounds from fmriprep: which one would you use for GLM?

Opinions on this topic are divided and this is why FMRIPREP provides those regressors instead of cleaning up the data for you. I personally would include 6 motion parameters, FD, and aCompCor on run level and mean FD on group level (for both task and rest).

Could you clarify what you mean by re-introducing noise? Are mean FD + age your covariates in your partial correlation?

@arwang

Any potential for re-introducing noise if, for example, I include mean FD + age in a partial correlation between functional connectivity and a behavioral measure?