Could a self-initiated neuroelectrical event represent a large-scale form of “volume transmission”? (Case: Spontaneous Neuroelectrical Cascade)

Dear colleagues,

I’d like to share a conceptual hypothesis based on first-person neurophysiological observations across 1,000 reproducible events, termed Spontaneous Neuroelectrical Cascades (SNCs).

These are wave-like, self-initiated neuroelectrical events that propagate throughout the body under full awareness, sometimes triggered by subtle modulation of intracranial pressure (ICP). Physiological markers include mild tremors, sweating, salivation, and a sensation of electrical flow.

I hypothesize that the SNC may represent a macro-scale form of “volume transmission” — an electrical wave that propagates through neural and cerebrospinal tissue beyond direct synaptic connections, potentially serving as a self-regulatory reset mechanism of the nervous system.

Questions for discussion:

  • Could such a phenomenon fit within existing models of non-synaptic or volume-based transmission?
  • Which experimental methods (EEG, MEG, NIRS, CSF ion flux studies) could best capture large-scale field coherence during such events?
  • Are there known analogs of self-initiated, non-pathological neuroelectrical cascades in current literature?

References:

  • OSF preprint: https://osf.io/p4vkx
  • Related discussion: LinkedIn — “A New Window Into Brain Self-Regulation”

Any theoretical or methodological feedback would be greatly appreciated.

Thank you,
Triệu Vỹ Nguyễn
Independent Researcher
Ho Chi Minh City, Vietnam

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