Hi @sameera2004 –
Unfortunately, we don’t recommend this pipe-lining of the two methods – the distortion correction applied in fMRIPrep invalidates the calculation of the T2* map that underlies tedana’s optimal combination and denoising procedures. Instead, we recommend using files from the fMRIPrep working directory. Please see this thread for more details: Combining fmriprep with ME-ICA from tedana
HTH,
Elizabeth