Calculating Mutual Information between two images prior transformation with dipy

Hi all,

I am looking for guidance to calculate the MI between two unregistered images prior to any transformations with dipy. I have looked through documentation but have yet to figure out what to input for the transform argument for MutualInformation.setup.

Thanks in advance for your help,

Thanks for your question! I believe that one input here could be an instance of the AffineTransform class. You can initialize this with an identity transform by giving it an np.eye(3) (if your images are 2D) or np.eye(4) (if your images are 3D).

I haven’t tried this myself, though. So I am not 100% sure this would work. Let me know if you run into issues.

[Edited to fix a typo]