I am currently using MRIQC to check imaging data quality. I find there is one option to include despike in MRIQC. Does it mean imaging data after MRIQC are “despiked”. I am suggested to not run despike before head motion estimation, which is included in fMRIPrep. So I wonder, does it matter that I put despike in MRIQC, then run fMRIPrep (it seems despike cannot be done in fMRIPrep) for pre-processing, and use confounds in generated tsv files for further data analysis? Any suggestion or help is welcome! Thanks in advance!