I would also like to regress out WM and CSF from the nonaggressive denoised data. @oesteban, you wrote
And still, if you use ICA-AROMA I would discourage using the CompCor regressors as they can effectively reintroduce some of the noise variance.
Do you also discourage regressing out mean time series of WM and CSF from AROMA’s nonaggressive denoised data? Because I thought that was the original recommendation in the Pruim et al paper, wasn’t it? And also the first scenario suggested here.