The Virtual Brain (TVB) Edu Pack for clinical case studies reports
TheVirtualBrain (TVB, thevirtualbrain.org), is an open-source platform to model large-scale brain
networks by merging different data sources in a dynamical systems framework.
One of its unique characteristics is the combination of a very powerful set of core functions (written in Python and C++), and a user-friendly web interface, most convenient for educational purposes and dissemination to a wide community.
TVB has already been successfully employed in a wide range of case studies, including different
experimental paradigms in healthy subjects, and different types of brain diseases.
A key feature of TVB is the possibility of implementing models of neural activity on the structural
architecture of individual brains, and fit these models to the actual brain activity of each subject.
This process is called “virtualization”, and is particularly relevant (actually absolutely necessary) in clinical studies involving patient-specific lesions, such as stroke and brain tumour.
To facilitate the reproducibility of these results, and to provide robust starting points for further
research, we aim to build a set of webpages containing all the information to reproduce clinical
applications, including videos of the workflow from a GUI perspective, and notebooks with code.
In line with the coding spirit of GSoC, the student will have to perform purely coding work (mainly in Python to build the notebooks), without having necessarily to understand the clinical cases and the details of the computational models. Of course we will be happy to discuss and develop these latter aspects as well for students who are interested.
NB, small changes were made to this text on Feb 27, on request of the mentors.
Technical keywords: Python, C++, XML, SQL, HTML