iEEG in white matter

Hi, everyone. In SEEG, clinicians always don’t analyze the signal in the white matter, why is that? Does anyone know some tutorials about this?

As I know, whiter matter consists of white matter fiber tracts. The function of fiber tracts is like a signaling pathway across different cortex regions. Is this that simple? Because in some paper said the iEEG in the white matter might be useful.

And the iEEG in the white matter always has more high-frequency signal, why is that?


Similar questions have been asked for BOLD signal in white matter. Not sure if relevant to your field, but a recent paper looked into resting state BOLD signal in white matter voxels and found a distinct characteristic signal.

Thank you for your reply. I’m going to look into this.

Cool. If you find anything interesting, let me know. We have some resting state data of our own that I would love to analyze for this!