NODDI for single-shell DWI

1

Hello everyone,

I am working with a dataset that is single-shell DWI. I know that standard NODDI is designed for multi-shell DWI, so I wanted to ask if there are any methods for estimating NODDI-like metrics from single-shell data that are considered standard practice and reliable, or whether they should still be treated as experimental.

Thank you in advance!

2

Hi @lavender99 and welcome to neurostars!

I would consider all of them experimental, but there is this to try: Single-shell NODDI using dictionary-learner-estimated isotropic volume fraction - PubMed ( GitHub - abrarfaiyaz/DictNet: Stochastic Sparse Dictionary based Learner · GitHub )

Best,

Steven

3

Hi @Steven,

Thank you for your response! I’ll look into your suggestion.