Trying to extract ROI texture features from T1 scans registered to MNI152 with fMRIPrep/ANTs

To extract texture features from specific ROI using PyRadiomic, I tried two different methods:

  1. Use fMRIPrep with --anat-only option

  2. Simply run a Nipype workflow with RegistrationSynQuick interface

This is the distribution of one features across all subjects:


I’m wondering what might be the reason why images processed by fMRIPrep have a different distribution with smaller variance. Should I use sMRIPrep instead?

Here are two images from the same subject with different methods: