White matter hypointensity in T1. MPRAGE using Freesurfer

Dear Neuroimagers,
Can we rely on T1 MPRAGE for defining white matter lesions using the hypointensity segmented using Freesurfer? I know it would be better to have FLAIR but this is how the data has been collected and the analysis is gonna be retrospective!!

This paper may be of interest for answering your question:

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