I am watching Adam Cohen’s lecture from Youtube. It seems like it’s still far behind from Calcium imaging like @pachitarium and @carsen.stringer are doing. However, with the example he shows, it seems like they could get more than single spike temporal resolution. I thought the reason that Calcium imaging can’t get single spike resolution is because the signal’s too small so that it needs more integration time. If the signal’s big enough, theoretically Calcium imaging could get single spike resolution too. I don’t understand why it’s not the case for voltage imaging.